Agentic Scientific Machine Learning
Speaker
George Em Karniadakis
The Charles Pitts Robinson and John Palmer Barstow Professor of Applied Mathematics, Brown University MIT and PNNL
Title
"Agentic Scientific Machine Learning "
Abstract
Scientific Machine Learning (SciML) integrates data-driven inference with physical modeling to solve complex problems in science and engineering. However, the design of SciML architectures, loss formulations, and training strategies remains an expert-driven research process, requiring extensive experimentation and problem-specific insights. We introduce AgenticSciML, a collaborative multi-agent system in which over 10 specialized AI agents collaborate to propose, critique, and refine SciML solutions through structured reasoning and iterative evolution. The framework integrates structured debate, retrieval-augmented method memory, and ensemble-guided evolutionary search, enabling the agents to generate and assess new hypotheses about architectures and optimization procedures.
Across physics-informed learning and operator learning tasks, the framework discovers solution methods that outperform single-agent and human-designed baselines by up to four orders of magnitude in error reduction. The agents produce novel strategies -- including adaptive mixture-of-expert architectures, decomposition-based PINNs, and physics-informed operator learning models -- that do not appear explicitly in the curated knowledge base. These results show that collaborative reasoning among AI agents can yield emergent methodological innovation, suggesting a path toward scalable, transparent, and autonomous discovery in scientific computing.
About Speaker
George Karniadakis is from Crete. He is an elected member of the National Academy of Engineering, National Academy of Arts and Sciences, and a Vannevar Bush Faculty Fellow. He received his S.M. and Ph.D. from Massachusetts Institute of Technology (1984/87). He was appointed Lecturer in the Department of Mechanical Engineering at MIT and subsequently he joined the Center for Turbulence Research at Stanford / Nasa Ames. He joined Princeton University as Assistant Professor in the Department of Mechanical and Aerospace Engineering and as Associate Faculty in the Program of Applied and Computational Mathematics. He was a Visiting Professor at Caltech in 1993 in the Aeronautics Department and joined Brown University as Associate Professor of Applied Mathematics in the Center for Fluid Mechanics in 1994.
After becoming a full professor in 1996, he continued to be a Visiting Professor and Senior Lecturer of Ocean/Mechanical Engineering at MIT. He is an AAAS Fellow (2018-), Fellow of the Society for Industrial and Applied Mathematics (SIAM, 2010-), Fellow of the American Physical Society (APS, 2004-), Fellow of the American Society of Mechanical Engineers (ASME, 2003-) and Associate Fellow of the American Institute of Aeronautics and Astronautics (AIAA, 2006-). He received the William Benter award (2026), the SES G.I. Taylor medal (2014), the SIAM/ACM Prize on Computational Science & Engineering (2021), the Alexander von Humboldt award in 2017, the SIAM Ralf E Kleinman award (2015), the J. Tinsley Oden Medal (2013), and the CFD award (2007) by the US Association in Computational Mechanics. His h-index is 160 (highest in Applied Mathematics) and he has been cited over 156,000 times.
https://sites.brown.edu/crunch-group/