Today more than ever, it’s clear that everything depends on our health.
Collaborating across all disciplines, NYU Tandon has been working at the intersection of engineering, healthcare, and life sciences for decades, and our researchers have the expertise to create next-generation solutions at every scale.
Meeting health challenges with innovative solutions
We combine far-reaching research geared towards longstanding clinical problems with Apollo 13 mindsets that enable us to create rapid responses to new medical challenges as they emerge. Being Tandon Made means being ready for the future now, because we don’t believe in waiting until a crisis hits to make good health a priority.
Finding ways to make the world healthier
Professor Yao Wang is a recognized expert in video coding, networked video applications, medical imaging and telehealth, and computer vision. She holds a joint appointment in Tandon’s Department of Electrical and Computer Engineering and Department of Biomedical Engineering, and she has an affiliated appointment in the Radiology Department of NYU’s School of Medicine.
S. Farokh Atashzar is an Assistant Professor of Electrical and Computer Engineering, as well as Mechanical and Aerospace Engineering, and he leads the school’s Medical Robotics and Interactive Intelligent Technologies (MERIIT) Laboratory, whose mission is to develop and implement artificial intelligence, advanced control systems, signal processing algorithms, smart wearable mechatronic modules, and transparent human-robot interaction systems to augment human capabilities. A particular focus of the lab is on interactive Neuro-Rehabilitation Robotic and Surgical Robotic systems.
Research Labs & Groups
Advanced Ophthalmic Imaging Laboratory (AOIL)
The AOIL consists of a team of ophthalmologists, engineers, software specialists, statisticians, and trainees that focus primarily on the study of glaucoma, a leading cause of blindness in the world. The groups of Profs. Schuman, Wollstein and Ishikawa develop advanced imaging tools to detect this disease, monitor its progression, and investigate its pathogenesis.
Applied Dynamics and Optimization Laboratory
We aim to establish mathematical models, quantitative criteria, and algorithmic/computational foundations toward their implementations in robotics (for design and control), biomechanical systems (for prediction and analysis), and their intersections such as lower-body wearable robots. Our current research topics include energetics of dynamic systems, legged balance and gait stability, and integration of dynamics/control with numerical optimization.
Applied Micro-Bioengineering Laboratory (AMBL)
Taking advantage of state-of-art nanotechnologies and fabricating fascinating functional biomaterials and integrated biosystems, the Professor Weiqiang Chen’s laboratory addresses numerous important problems in fundamental biology as well as clinical applications in disease diagnosis and treatment.
Bio-interfacial Engineering and Diagnostics Lab
Levicky Group — The Bio-interfacial Engineering and Diagnostics Group’s research focuses on quantitative characterization of biomolecular interactions, with technological connections to diagnostics for medical and fundamental biology applications. The group seeks to dissect the fundamental equilibrium and kinetic aspects of biomolecular reactions at surfaces and in solution, elucidate the role played by the molecular organization, and apply this understanding to advance bioanalytical technologies.
The laboratory of Professor Jef Boeke is well known for foundational work on mechanistic and genomic aspects of retro-transposition in both yeast and mammalian systems. After more than three decades, they continue to scrutinize their favorite genomic parasites. In addition, the Boeke lab is heavily involved in the development of novel technologies in genetics, genomics and synthetic biology.
Cell Programming and Genome Engineering Lab
David Truong’s lab uses principles from synthetic and systems biology, cell fate reprogramming, epigenetics, and immunology. He and his team perform large-scale genome engineering in human and mouse stem cells towards cell therapies and regenerative medicine. The group currently focuses on developing programmable off-the-shelf dendritic cells from human iPSCs as a cancer immunotherapy platform. They are also building universal “personalized” iPSCs as an off-the-shelf cell for making living therapies.
Center for Advanced Imaging Innovation and Research
Professor Dan Sodickson’s research primarily addressed the development of new techniques for biomedical imaging to improve human health. He leads a multidisciplinary team that develops new methods for rapid continuous imaging, taking advantage of recent developments in parallel imaging, compressed sensing, and artificial intelligence. This work extends to clinical applications of MRI, PET and CT.
The overarching goal of our research is to develop the principles needed to incorporate unstructured, Internet and mobile data into a better understanding of population-level health. We primarily develop computational methods across data mining, natural language processing, and machine learning to generate features for spatio-temporal population-level public health models.
Clinical Biophotonics Laboratory
Professor Andreas Hielscher’s team focuses on developing clinically relevant optical tomographic imaging systems. They apply these devices and wearable electronics to the diagnosis and treatment of various diseases, such as breast cancer, arthritis, peripheral artery disease, diabetic foot syndrome, and real-time monitoring of brain activities.
Computational Medicine Laboratory
Professor Rose Faghih group develops biomedical signal processing and control algorithms for human-technology interactions and monitoring. These state-of-the-art tools are employed for prognosis, diagnosis, and treatment of pathological conditions related to neuro-endocrine and neuro-psychiatric disorders.
Computational Neuroscience, Neuroengineering, and Neuropsychiatry Laboratory (CN3)
The research in Professor Sage Chen’s lab aims to find solutions for real-time brain-machine interfaces, pain management, and psychiatric disorders. Developing a better understanding of memory and sleep is another goal. To accomplish all this, they advance and integrate the fields of computational neuroscience, neural engineering, and machine learning.
Craniomaxillofacial Orthopedic Biomaterials Regenerative Applications Lab
Professor Lukasz Witek’s research group performs in vivo and in vitro evaluations of a wide range of (bio)materials that can be used as implants for dental and orthopedic applications. A special focus is on 3D printing of bio-ceramic materials for tissue regeneration.
CUSP Urban Observatory (CUSP-UO)
Through the novel use of observational and analytical techniques, the Urban Observatory at the Center for Urban Science + Progress (CUSP-UO) studies the complex interactions between the physical, natural, and human components of the city as a coherent, definable system with the goal of enhancing public well-being, city operations, and future urban plans.
What are the causes and consequences of genomic copy number alterations (i.e. aneuploidy) in cancer and how does this affect patients’ response to therapy, especially immuno-therapy? These are among the main questions Prof. Teresa Davoli’s lab is interested in. To answer these questions, they utilize a variety of experimental and computational approaches, from large- scale genetic screens in human cells, to prediction of survival in cancer patients.
Dynamical Systems Laboratory (DSL)
Professor Maurizio Porfiri’s group conducts multidisciplinary research in the theory and application of dynamical systems, motivated by the objectives of advancing engineering science and improving society. Their theoretical expertise is in controls, networks, nonlinear dynamics, and time-series, while our application domain is in modeling and analysis of physical, social, and technical systems.
Using advances in computer vision and machine learning, Professor Guido Gerig’s team develops image analysis methodologies related to segmentation, registration, atlas building, shape analysis, and image statistics. Collaboratively with clinical research, this work is driven by medical problems covering research in autism, Down's syndrome, eye diseases, Huntington's disease, and musculoskeletal disorders.
Todd Hudson is a computational neuroscientist whose research focuses on modeling sensory and motor systems, particularly eye and arm movements in healthy and disease states. He received his training at the Clarence Graham Memorial Laboratory of Visual Science at Columbia University, and co-founded Tactile Navigation Tools, LLC, a company that develops navigation aids for the visually impaired.
Hybrid Nanomaterials Lab
Sahu Group — Our research investigates the transport phenomena in new and novel classes of nanostructured hybrid materials that have promise for optoelectronic and thermoelectric energy conversion. Our group has expertise in colloidal synthesis, advanced characterization, and device implementation of such materials.
Integrated BioElectronics Laboratory
Professor Sohmyung Ha’s lab aims at advancing the engineering and applications of silicon integrated technology interfacing with biology. This is approached in a variety of forms, ranging from implantable biomedical devices to unobtrusive wearable sensors.
The ultimate goal of Professor Kirsch’s research is to define novel therapeutic targets for the treatment of osteoarthritis and other joint diseases and injuries. To this end the laboratory studies mechanisms involved in the regulation of cartilage homeostasis, maintenance and pathology. In addition, research is performed on how cells and the joint environment interact.
Laboratory for Advanced Neuroengineering and Translational Medicine
Professor Khalil Ramadi and his team develop innovative approaches for the modulation of neural activity throughout the body. The goal is to come up with novel therapies for neurologic, metabolic, and immune disorders. They combine mechanical, electrical, materials, and bio-engineering toolkits in the design of minimally invasive technologies.
Laboratory for Biomechanics, Mechanobiology & Regenerative Medicine
Professor Alesha Castillo and her team study the interactions between mechanobiological cues and musculoskeletal systems with the long-term goal of developing novel biophysical, pharmaceutical, and stem cell-based interventions to improve musculoskeletal health
Laboratory for Personalized Immunotherapies
Personalized immunotherapies involving CAR T cells, TCRs and BiTEs, have revolutionized the treatment of cancer. They provide in cures in subsets of cancer patients, yet remain ineffective for the majority of patients. Prof. Mark Yarmarkovich aims to expand the use of curative immunotherapies. To this end, his group develops and employ technologies at the intersection of genomics, proteomics, immunology, antibody engineering and computational biology.
Laboratory of Computational Multiomics
Professor Ruggles’ laboratory focuses on understanding human health and biology using data science, data visualization, and predictive modeling. A primary goal of this research is to analyze and integrate diverse data modalities, including bulk and single-cell sequencing, phospho- and global- proteomics, metagenomics, flow cytometry, imaging, and clinical data. These multi-omic methods are used to better understand cancer, heart diseases, and other disorders.
Laboratory of Computational Proteomics
Prof. David Fenyö’s uses proteomic approaches to develop methods to identify, characterize, and quantify proteins important for various cellular processes. His efforts to integrate data from multiple technologies - including mass spectrometry, sequencing, and microscopy - have provided a wide array of powerful tools to discover and verify biomarkers and therapeutic targets in cancer.
To respond to a changing environment, cells have to express the right genes at the right time. Professor Timothy Lionnet’s lab tries to understand how exactly this is achieved and how robust responses emerge from random molecular events. Getting insights into these biomolecular processes will ultimately provide new tools to tackle, for example, wound healing, cancer, and many other diseases.
Micro- and Nano-scale Bioengineering Lab
The research in the Professor Yong-Ak (Rafael) Song’s group at NYU-AD lies at the interface between biology, physics and engineering. More specifically, their research is focused on applying microfluidics and nanofluidics to broad range of challenges in bioscience and medicine.
Montclare Lab for Protein Engineering and Design
We focus on engineering macromolecules. We aim to predictably design or engineer artificial therapeutics, biocatalysts, scaffolds and cells.
NanoBioEngineering for tissue reprogramming and regeneration
Our lab designs, develops, and applies nanoscale and bioengineering tools to understand and manipulate cell fate and function. Our ultimate goal is to help the body regenerate better.
The Nanofabrication Cleanroom provides academic and industry researchers with access to the equipment and expertise needed to leverage cutting-edge nanotechnology and produce the materials necessary to advance their science, regardless of their department, sector, or vision.
Nanooptical Bioengineering Lab
Hoagang Cai’s lab advancec nanotechnology for biological and biomedical applications. Employing nanolithographic technology, his group creates designer biomaterials and metasurfaces with unprecedented precision and functionality. Applications range from studying T-cell activation in cancer treatment to photo-stimulation in optogenetics and brain research.
Network Dynamics and Synthetic Biology Group
Blending theory with experiments, Professor Andras Gyorgy’s team focuses on the behavior of networks with particular emphasis on synthetic biology applications.
Neural Circuits and Algorithm Group
The aim of Dr. Chklovskii’s research is to understand how the brain analyzes large and complex datasets streamed by sensory organs. Informed by anatomical and physiological neuroscience data, his group develops algorithms that model brain computation and solve machine learning tasks. The overarching goal it to build artificial neural systems and treating mental illness.
Neural Interface Engineering Lab
The team of Professor Shy Shoham works at the interface of neuroscience and engineering, developing and applying modern bidirectional neural interfaces for observing and controlling neural population activity patterns. Their goal is to better understand sensory-motor information coding and to advance medical neurotechnology.
Neuroimaging and Visual Science Laboratory
Kevin Chan and his group are developing and applying new methods for noninvasive imaging of neurodegeneration, neurodevelopment, neuroplasticity, and neuroregeneration in people with vision-related diseases and injuries. They study the structural, metabolic, physiological, and functional relationships between the eyes, brain, and behavior with the mission to improve vision.
NYU Ability Project
An interdisciplinary initiative dedicated to the study of disability and the development of accessible, assistive and rehab technologies.
Our research team studies the physics of electronic materials and their application in building devices and circuits. We are an experimental group with experience in the synthesis of layered materials, nanofabrication of electronic devices, and electrical measurements at both room and cryogenic temperatures.
NYU Video Lab
Research activities in Professor Yao Wang’s group deal with encoding and distributing videos among a large number of users. Of special interest are diverse network access links and applications to biomedical imaging. The lab collaborates extensively with other research groups in wireless communication and networking at the School of Engineering and NYU’s medical school and hospitals.
Pain Management Laboratory
The human experience of pain is incredibly complex. Understanding how pain affects patients, and how best to manage it, is Prof. Jing Wang’s goal. His research interest is centered on the role of brain circuits in the regulation of acute and chronic pain. Of particular interest are the cortical mechanisms of pain processing and regulation.
Perception and Brain Dynamics Laboratory
Every day, our brains cycle through different states of awareness: from the rich conscious experiences during wakefulness to dreamless sleep to the bizarre experiences during dreaming sleep. Understanding the neural basis of conscious awareness is the basic goal of Prof. Biyu He’s team. She is using a combination functional magnetic resonance imaging (fMRI), magneto- encephalography (MEG) and invasive electrophysiology to explore relevant neural mechanisms and characterize various neuropsychiatric illnesses.
Physical Therapy and Exercise Lab
Professor Smita Rao and her colleagues in the Center of Health and Rehabilitation Research study the effects of exercise in individuals with diabetes, neuropathy, osteoarthritis, and other musculoskeletal conditions. Her research focuses on improving physical therapy and rehabilitation care in these patients.
Pinkerton Research Group
Focuses on developing responsive soft materials for biomedical applications. The group uses tools from chemical and materials engineering, nanotechnology, chemistry and biology to create functional soft materials via scalable synthetic processes and to understand the material behavior in biological systems.
Advances in miniaturized sensors and actuators, as well as artificial intelligence (AI), have broadened horizons for assistive and rehabilitative technologies. The team of Professor JohnRoss Rizzo, MD, is leveraging these innovations to help patients with conditions such as blindness and stroke, enhancing their ability to interact physically with their environment.
In the laboratory of Professor Ivan Selesnick, PhD, researchers are interested in digital signal processing, sparsity in signal processing, and multi-dimensional wavelet-based signal/image/video processing. They develop new methods for signal filtering, separation, and deconvolution, especially in the area of biomedical imaging.
Shukti Chakravarti Lab
Professor Chakravarti’s research group tries to understand how the extracellular matrix (ECM) regulates cellular functions and tissue homeostasis. In their work they use cell cultures and mouse models to gain a better understanding of the role of neutrophil, macrophage and dendritic cell functions in bacterial and viral infections. In addition, they explore the ECM changes and the underlying genetic causes in corneal diseases.
Single Molecule Biophotonics Laboratory
Prof Eli Rothenberg’s team specializes in development of cutting-edge single-molecule fluorescence imaging techniques. They apply these techniques to studying molecular mechanisms relevant to diverse human diseases, including cancer. Adding novel computational methods and assays they aim to discover biomarker, therapeutic targets, and understand drug mechanisms-of-action.
Smilow Comprehensive Prostate Cancer Center (SCPCC)
The work that Professor Samir Taneja and his colleagues are conducting at NYU Langone’s SCPCC and Perlmutter Cancer Center has transformed the field of prostate cancer diagnosis and therapy. Their clinical research focuses on the use of MRI to improve methods of prostate imaging, cancer detection, disease localization, and treatment.
Social Behavior Neuroscience Lab
Social behaviors such as fighting, defense, and parenting, are innate and ubiquitous across the animal kingdoms. The research in Dr. Lin’s laboratory centers on understanding the neural circuits underlying these behaviors. Various genetic engineering, tracing, functional manipulation, in vivo electrophysiological recording and computational tools are combined to dissect the neural circuits in a great detail.
Speech Language Electrocortiography Laboratory
How is language produced and perceived in the human brain? What are the network dynamics that allow us to fluently communicate? These questions are still poorly understood and collaborations between scientists, clinicians, and engineers are crucial for making progress in this fascinating field. Adeen Flinker and his team are using unique human neurosurgical recordings and advanced data processing algorithms to elucidate these questions.
Tissue Maintenance and Regeneration Laboratory
Tissue maintenance and regeneration are crucial for preserving tissue functionality and organismal health. With age and disease, both of these processes can become inefficient. Professor Wosczyna’s laboratory seeks to identify cellular mechanisms that are responsible for pathological phenotypes. They look for molecular targets that can be modified to extend tissue functionality further into age.