Biomechanics, Biosystems, and Bioengineering

Many exciting topics exist at the interface between biology and micro/nanotechnology. Taking advantage of state-of-art nanotechnologies and fabricating fascinating functional biomaterials and integrated biosystems, we can address numerous important problems in fundamental biology as well as clinical applications in disease diagnosis and treatment. Our research is mainly focusing on interdisciplinary researches that leveraging the engineering advances in biomaterials, microfluidics and advanced manufacturing for new and better solutions for emerging problems in cancer biology, systems immunology, and stem cell-based regenerative medicine. Specific examples include microengineered nanotopographic biomaterial for capture and analysis of the rare circulating tumor cells (CTCs) for cancer diagnosis, and synthetic micro/nanoscale ex vivo cellular microenvironment for study and regulating human embryonic stem cell behaviors that are desirable for functional tissue engineering and regenerative medicine. In addition to biomaterials, new microfluidic-based immunomonitoring platform has been explored for accurate measurement of the immune status in patients with immune system disorders such as HIV, sepsis, malaria and Tuberculosis. These novel micro/nanoengineered functional biomaterials and biosystems will not only permit advances in engineering but also greatly contribute to improving human health.

Muiltiple openings are available for postdoctoral fellow, graduate and undergraduate students in our lab. Please check Opening for more information.

Lab Gallery

Science seminar in the Mott Hall IV Middle School on May 9, 2018

Jimmy Yau MS thesis defense on May 4, 2018

Group photo on December 22, 2017

The 2017 Summer Undergradaute Research Team: Phoebe Welch, Levan Asatiani, Jiong Xian Huang, Zijing Zhang, Fang Ni Zeng, Adam Grozvirt-Dramen, Joyce Yan

The biophysics team in 2016 BMES Conference on October 6, 2016

Group photo on September 2, 2016

Group photo on June 12, 2015

Group dinner on June 12, 2015

Weiyi won the 2015 Best Mechanical Engineering PhD Qualifying Exam Performance Award

2015 Summer Undergradaute Research Participant Ahmed Aladly (from the New Jersey Institute of Technology) Working in the Lab


May 4, 2018
Jimmy passed his MS thesis defense. Congratulations!

April 25, 2018
Dr. Chen gave an invited talk in the 2018 IEEE International Conference on Nano/Micro Engineered and Molecular Systems(IEEE NEMS 2018) in Singapore.

April 9, 2018
Renee-Tyler Tan Morales were awarded theAmerican Heart Association Undergraduate Student Summer Fellowship Award! Congratulations!

January 29, 2018
Our study of "Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis" is published in Biomaterials!

January 16, 2018
Our study of "Nanotopography Regulates Motor Neuron Differentiation of Human Pluripotent Stem Cells" is published in Nanoscale!

January 12, 2018
Our collaboritive study of "A fluorescent microbead-based microfluidic immunoassay chip for immune cell cytokine secretion quantification" is published in Lab on a Chip!

January 8, 2018
We welcome our new postdoc Jie Tong to join our Lab!

January 6, 2018
Dr. Chen gave an talk in the 2018 Cellular and Molecular Bioengineering Conference (CMBE 2018) in Key Largo, Florida.

December 11, 2017
Dr. Chen gave an invited talk in the 3rd International Symposium on Mechanobiology (ISMB 2017) in Singapore.

Novermber 16, 2017
Our study of "Nanotopographic Regulation of Human Mesenchymal Stem Cell Osteogenesis" is published in ACS Applied Materials & Interfaces!

August 22, 2017
Dr. Chen were awarded the NYU Goddard Junior Faculty Fellowship!

August 1, 2017
We welcome our new postdoc Chao Ma to join our Lab!

July 14, 2017
Dr. Chen chaired an Invited Session of "Microfluidic Systems for Cell Manipulation and Analysis" in the 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society in the Jeju Island, Korea.

July 13, 2017
Dr. Chen were awarded the NYU Whitehead Fellowship! The award will support out research on developing Glioma-on-a-Chip for in vitro Validation of Personalized Immunotherapyis.

July 5, 2017
We were awarded the NSF grant to develop Plasmofluidic Nanoantenna-Superlens Biosensor for Single-Cell Functional Immunophenotyping! NYU Tandon News: Understanding the Immune System on a Nano-scale

June 21, 2017
Our collaborative reserarch project "Nanomechanical Phenotyping of Prostate Circulating Tumor Cells" with Profs. Qasaimeh at NYU Abu Dhabi was supported by the NYUAD Research Enhancement Fund!

June 1, 2017
We welcome our new postdoc Jingyi Zhu and Haoyu Wang to join our Lab!

April 11, 2017
Xin gave an invited talk in the IEEE NEMS 2017 Conference in Los Angeles.

April 10, 2017
Dr. Chen chaired and gave an invited talk in the 1st NYU Biomedical and Biosystems Conference in NYU Abu Dhabi.

March 13, 2017
Our collaborative reserarch project with Profs. Matija Snuderl and Luisa Cimmino in the Department of Pathology was supported by the NYU mega-grant initiative award from the NYU Provost Office! The goal of this project is to bioengineer in vitro glioma microenvironment model for personalized immunotherapy.

February 15, 2017
We were awarded the NYU CTSI Translational Research Pilot Project Award for our collaborative reserarch project with Prof. Jose Aleman at the School of Medicine to develop new plsamo-microfluidic biosensing chip for single-cell phenotyping of human adipose tissue immune cells.

November 1, 2016
Dr. Chen gave an invited talk in the IEEE-NANOMED conference in Macau, China.

October 10, 2016
We welcome our new visiting PhD student Xin Sui to join our Lab!

October 5-8, 2016
Qianibn and Weyi presented their research in the 2016 BMES Conference.

July 4, 2016
We welcome our new postdoc Xin Cui to join our Lab!

May 20, 2016
We were awarded the American Heart Association Scientist Development Grant! The goal of this project is to study the nanotopography-dependent neural induction of human induced pluripotent stem cells.

March 10, 2016
We were awarded the NYU Global Seed Grant for Collaborative Reserarch with NYU Abu Dhabi (Prof. Qasaimeh) to develop new plsamonic biosensing chip for single cell phenotyping!

Jan 28, 2016
AMB Lab welcomes his newest postdoc, Qianbin, welcome on board!

April 27, 2015
Congratulations to Weiyi! He has just won the Best Mechanical Engineering PhD Qualifying Exam Performance Award!

March 9, 2015
Congratulations to Weiyi! His first review paper on microfluidics-based capture of CTCs has just been accepted by Small!

February 26, 2015
Weiqiang has just won the UM ProQuest Distinguished Dissertation Award!

February 12, 2015
Congratulations to Weiyi! He has successfully passed ME Ph.D. qualifying exam!

December 20, 2014
AMB Lab welcomes Andrew, Nasir and Lanqi to join our Lab!

December 11, 2014
AMB Lab welcomes our new gradaute student, Affan to join our Lab. welcome on board!

September 1, 2014
AMB Lab welcomes his newest doctoral students. Weiyi and Yan, welcome on board!

September 1, 2014
Weiqiang has joined the Department of Mechanical and Aerospace Engineering of New York University as an assistant professor!