Nanoenhanced Biosensor Detects Single Proteins
- photonics.com July 25th, 2013
- Source: http://www.photonics.com/Article.aspx?AID=54485
The microcavity biosensor that set a record by detecting the smallest single virus in solution has reached a new breakthrough: detecting a single label-free cancer marker protein. The achievement, which shatters the previous record and sets a new benchmark for the most sensitive limit of detection, may significantly advance early disease diagnostics.
In 2012, Stephen Arnold of Polytechnic Institute of New York University (NYU-Poly) and colleagues at Fordham University and New York City College of Technology developed a novel microcavity biosensor treated with plasmonic gold nanoreceptors, which enhance the electric field of the sensor and allow even the smallest shifts in resonant frequency to be detected.