Discovery of new materials provides moments of inspiration and shifts in understanding, shaping the dynamic field of materials science. Following the graphene breakthrough, many other 2D materials emerged. Although many of them remain subjects of purely academic interest, others have jumped into the limelight due to their attractive properties, which have led to practical applications. Among the latter are 2D carbides and nitrides of transition metals known as MXenes. The family of MXenes has been expanding rapidly since the discovery of Ti3C2 in 2011. More than 30 different stoichiometric MXenes have been reported, and the structure and properties of numerous other MXenes have been predicted. Moreover, the availability of solid solutions on M and X sites, multi-element high-entropy MXenes, control of surface terminations, and the discovery of out-of-plane ordered double-M o-MXenes (e.g., Mo2TiC2), as well as in-plane ordered i-MAX phases and their i-MXenes offer a potential for producing dozens of new distinct structures. This presentation will describe the state of the art in the manufacturing of MXenes, their delamination into single-layer 2D flakes and assembly into films, fibers and 3D structures. Synthesis-structure-properties relations of MXenes will be addressed on the example of Ti3C2. The versatile chemistry of the MXene family renders their properties tunable for a large variety of applications. In particular, the interaction of MXenes with electromagnetic waves can be controlled via their composition and structure. Many MXenes offer high electronic conductivity and outstanding electromagnetic interference shielding. They can also be used in telecommunication, energy, medical and electronic device applications.