Ryan L. Hartman

Ryan L. Hartman

Assistant Professor

Chemical and Biomolecular Engineering


Ryan L. Hartman is Assistant Professor in the Department of Chemical and Biomolecular Engineering.  He completed his postdoctoral research in the Department of Chemical Engineering at the Massachusetts Institute of Technology, Cambridge.  He earned his Ph.D. and M.S.E. in Chemical Engineering from the University of Michigan, Ann Arbor and his B.S. in Chemical Engineering from Michigan Technological University, Houghton.

Hartman’s laboratory investigates flow chemistry with microsystems using chemical reaction engineering principles for sustainable chemicals, energy, and healthcare.  His laboratory’s research has been featured in Chemical & Engineering Technology, Industrial & Engineering Chemistry Research, the Journal of Flow Chemistry, Organic Process Research & Development, Lab on a Chip, Reaction Chemistry & Engineering, and at conferences and seminars worldwide.  He is the Reaction Engineering Programming Chair of the American Institute of Chemical Engineers.  He is also co-inventor of twelve U.S. Patents, sixteen U.S. Patent Applications, and his contributions have helped to enable natural gas production and the continuous manufacture of fine chemicals and pharmaceuticals.

Previously, Hartman was Assistant Professor and Reichhold-Shumaker Fellow in the Department of Chemical and Biological Engineering at The University of Alabama, Tuscaloosa.  He was recently honored as Visiting Assistant Professor of the Institut de Chimie de la Matiere Condensee de Bordeaux CNRS, Universite de Bordeaux.  He is also a winner of the NSF CAREER Award and member of the National Academy of Inventors.  Undergraduate researchers in his laboratory have won prestigious honors, such as the NSF Graduate Research Fellowship Program Award and the Barry M. Goldwater Scholarship and Excellence in Education.  Students K-12 have also gained local, state, national, and international recognition for their senior thesis research in his laboratory.  Hartman returned to academia following his private sector career with Schlumberger Limited.

Journal Articles

(selected recent)

Pinho, B. and Hartman, R.L. "Microfluidics with in situ Raman spectroscopy for the characterization of non-polar/aqueous interfaces", React. Chem. Eng., (2016), DOI: 10.1039/c6re00177g.

Hu, C., Yen, A., Joshi, N., and Hartman, R.L. "Packed-bed Microreactors for Understanding of the Dissolution Kinetics and Mechanisms of Asphaltenes in Xylenes", Chem. Eng. Sci., 140, 144-152 (2016).

Hu, C., Shaughnessy, K.H., and Hartman, R.L. “Influence of water on the deprotonation and the ionic mechanisms of a Heck alkynylation and its resultant E-factors”, React. Chem. Eng., 1, 65-72 (2016).

Hu, C., Garcia, N., Xu, R., Cao, T., Yen, A., Garner, S., Macias, J., Joshi, N., and Hartman, R.L. "Interfacial Properties of Asphaltenes at the Heptol-Brine Interface", Energ. Fuel., 30 (1), 80-87 (2016).

Sabio, J.C., Domier, R.C., Moore, J.N., Shaughnessy, K., and Hartman, R.L. “Palladium theory of aqueous-phase Heck alkynylations for intensification of discovery and manufacture”, Chem. Eng. Technol., 38, 1717-1725 (2015).

Chen, Y., Sabio, J.C., and Hartman, R.L. “When solids stop flow chemistry in commercial tubing”, J. Flow Chem., 5 (3), 166-171 (2015).

Hu, C., Sabio, J., and Hartman, R.L. “Role of water on the precipitation and deposition of asphaltenes in packed-bed microreactors”, Ind. Eng. Chem. Res., 54 (16), 4103-4112 (2014).

Hu, C. and Hartman, R.L. “High-throughput packed-bed microreactors with inline analytics for the discovery of asphaltene deposition mechanisms”, AIChE J., 60, 3534-3546 (2014).

Hu, C., Morris, J.E., and Hartman, R.L. “Microfluidic investigation of the deposition of asphaltenes in porous media”, Lab Chip, 14, 2014-2022 (2014).

Domier, R.C. and Hartman, R.L. “Chemical reaction engineering perspectives on the role of water in fine chemicals and pharmaceuticals manufacture”, Chim. Oggi.-Chem. Today, 32 (4), 17-21 (2014).

Hu, C, Herz, C., and Hartman, R.L. “Microfluidic dispersion of mineral oil-seawater multiphase flows in the presence of dialkyl sulfonates, polysorbates, and glycols”, Green Process Synth., 2, 611-623 (2013).

Domier, R.C., Moore, J.N., Shaughnessy, K., and Hartman, R.L. “Kinetic analysis of aqueous- phase Pd-catalyzed, Cu-free direct arylation of terminal alkynes using a hydrophilic ligand”, Org. Process Res. Dev., 17 (10), 1262–1271 (2013).

Flowers, B.S. and Hartman, R.L. “Particle handling techniques in microchemical systems”, Challenges, 3, 194-211 (2012).

Hartman, R.L. “Managing solids in the upstream continuous processing of fine chemicals”, Org. Process Res. Dev., 16, 870–887 (2012).

Hartman, R.L., McMullen, J.P. and Jensen, K.F. “Deciding whether to go with the flow – evaluating the merits of flow reactors for synthesis”, Angew. Chem. Int. Ed., 40, 2-20 (2011).

Noel, T., Naber, J.R., Hartman, R.L., McMullen, J.P., Jensen, K.F. and Buchwald, S.L. “Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation” Chem. Sci., 2, 287-290 (2011).

Kuhn, S., Hartman, R.L., Sultana, M., Nagy, K.D., Marre, S. and Jensen, K.F. “Teflon-coated silicon microreactors: impact on segmented liquid-liquid multiphase flows”, Langmuir, 27, 6519-6527 (2011).

Hartman, R.L., Naber, J.R., Zaborenko, N. Buchwald, S.L. and Jensen, K.F. “Overcoming the challenges of solid bridging and constriction during Pd-catalyzed C-N bond formation in microreactors”, Org. Process Res. Dev., 14, 1347-1357 (2010).

Hartman, R.L., Naber, J.R., Buchwald, S.L. and Jensen, K.F. “Multi-step microchemical synthesis enabled by microfluidic distillation”, Angew. Chem. Int. Ed., 49, 899-903 (2010).

Hartman, R.L. and Jensen, K.F. “Microchemical systems for continuous-flow synthesis”, Lab Chip, 9, 2495-2507 (2009).

Hartman, R.L., Sahoo, H.R., Yen, B.C. and Jensen, K.F. “Distillation in microchemical systems using capillary forces and segmented flow”, Lab Chip, 9, 1843-1849 (2009).


Massachusetts Institute of Technology, Cambridge, 2010

Postdoctoral, Chemical Engineering

University of Michigan, Ann Arbor, 2006

Doctor of Philosophy, Chemical Engineering

University of Michigan, Ann Arbor, 2003

Master of Science in Engineering, Chemical Engineering

Michigan Technological University, Houghton, 2001

Bachelor of Science, Chemical Engineering


New York University

Assistant Professor of Chemical and Biomolecular Engineering

From: July 2015 to present

American Institute of Chemical Engineers

Reaction Engineering Programming Chair

From: February 2014 to present

The University of Alabama

Assistant Professor of Chemical and Biological Engineering

From: July 2010 to May 2015

Institute of Condensed Matter Chemistry (ICMCB-CNRS)

Visiting Assistant Professor

From: January 2015 to February 2015

Schlumberger Limited

Quality Steering Committee Chair, Chemical Engineer III

From: April 2005 to December 2007

BASF Corporation

Summer Chemical Engineering Intern

From: April 2000 to August 2000


U.S. Patent 9,238,772

U.S. Patent 8,802,601

U.S. Patent 8,765,646

U.S. Patent 8,763,623

U.S. Patent 8,752,627

U.S. Patent 8,496,056

U.S. Patent 8,490,698

U.S. Patent 8,435,387

U.S. Patent 8,210,249

U.S. Patent 8,119,574

U.S. Patent 8,008,234

U.S. Patent 7,789,146

U.S. Patent 7,784,541

Authored + Edited Books

Wolf, N. and Hartman, R.L. (editors), "Formation, Removal, and Inhibition of Inorganic Scale in the Oilfield Environment" by W. Frenier and M. Ziauddin, Society of Petroleum Engineers, 2008, 230 pp.

Awards + Distinctions


Invited Visiting Assistant Professor, Institut de Chimie de la Matiere Condensee de Bordeaux CNRS, Universite de Bordeaux

National Academy of Inventors

Schlumberger Inventor Award


American Association for the Advancement of Science (AAAS)

American Chemical Society (ACS)

American Institute of Chemical Engineers (AIChE)

American Society for Engineering Education (ASEE)

Flow Chemistry Society

International Society of Pharmaceutical Engineers

International Symposium on Chemical Reaction Engineering (ISCRE)

Materials Research Society (MRS)

Sigma Xi, The Scientific Research Society

Society for Petroleum Engineers (SPE)

Tau Beta Pi Engineering Honors Society

Research Interests

Catalysis and reaction engineering

Continuous-flow manufacturing

Flow chemistry

Microchemical systems

Molecular management

General / Collaborative Research

Anadarko Petroleum Company

Brookhaven National Laboratory

Brooklyn Technical High School, Brooklyn

Chevron Energy Technology Company

Eli Lilly and Company

Iowa State University

Nalco Champion, An Ecolab Company

Science and Mathematics Department, Alabama School of Fine Arts, Birmingham

Supercritical Fluids Group, Institut de Chimie de la Matiere Condensee de Bordeaux CNRS, Universite de Bordeaux


French National Research Agency (ANR), (U.S. Collaborator)
National Science Foundation (CAREER), (Principle Investigator)
National Science Foundation (CBET), (Principle Investigator)
National Science Foundation (EEC), (Senior Personnel)