Designer Binding Proteins for Biology, Medicine and Chemistry

Friday, February 9, 2018 - 10:30am - 12:00pm EST

  • Location:6 Metrotech Center, JAB 674
Shohei Koide, NYU Medical School

The main focus of our research group is to create proteins with novel functions, particularly proteins that selectively and potently bind to a predefined target molecule. Over the last two decades, we have advanced the fundamental knowledge and developed technologies for producing designer binding proteins. In particular, we have invented and refined the monobody system built on the scaffold of the fibronectin type III domain, which has been widely adopted in industry and academia. I will present the design principles underlying facile generation of designer binding proteins and their applications in diverse fields.